Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 16/20 | 0.78 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305142 | 0.82 | ENPP1 (0.74) | ENPP1ENPP3ENPP2 | |
| SCHEMBL24846968 | 0.80 | TDP1 (0.63) | ENPP1 | |
| SCHEMBL12635995 | 0.74 | SMN1; SMN2 (0.80) | ENPP1TSHRPOLB | |
| SCHEMBL20305097 | 0.74 | ENPP1 (0.79) | ENPP1ENPP3ENPP2 | |
| SCHEMBL20305107 | 0.73 | ENPP1 (0.73) | ENPP1ENPP3ENPP2TSHR | |
| SCHEMBL20687583 | 0.72 | ENPP1 (0.86) | ENPP1 | |
| SCHEMBL20679574 | 0.72 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL25481997 | 0.72 | TSHR (0.71) | TSHRPOLB | |
| SCHEMBL30675603 | 0.72 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL25482010 | 0.72 | LMNA (0.76) | TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ATEN PORUS LIFESCIENCES PVT. LTD. (IN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ENPP1, ENPP3, PNP | ENPP1 1/4885ENPP3 2/4885ENPP2 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.