Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | LDLR | P01130 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199902 | 1.00 | LMNA (0.36) | LMNANPC1TP53MAPK1RAB9A | |
| SCHEMBL200270 | 0.98 | ESR2 (0.36) | LMNANPC1TP53MAPK1RAB9A | |
| SCHEMBL199901 | 0.84 | PPARA (0.33) | LMNANPC1TP53MAPK1RAB9A | |
| SCHEMBL199881 | 0.84 | PPARA (0.33) | LMNANPC1TP53MAPK1RAB9A | |
| SCHEMBL200269 | 0.82 | GMNN (0.32) | LMNATP53MAPK1NPSR1CYP3A4 | |
| SCHEMBL202319 | 0.75 | SHBG (0.48) | LMNAESR2MIFESR1CYP3A4 | |
| SCHEMBL200881 | 0.75 | SHBG (0.48) | LMNAESR2MIFESR1CYP3A4 | |
| SCHEMBL200227 | 0.73 | SHBG (0.50) | LMNAESR2ESR1CYP3A4CYP2D6 | |
| SCHEMBL202011 | 0.71 | ESR1 (0.45) | LMNANPC1TP53MAPK1RAB9A | |
| SCHEMBL199652 | 0.70 | SHBG (0.50) | LMNANPC1RAB9AESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029573-B1 | DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS | BASF SE (DE) | 2011-10-26 | — | — | EP | disclosed |