Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846974 | 0.87 | ENPP1 (0.67) | ALDH1A1MAPTMAPK1ENPP1SMN1; SMN2 | |
| SCHEMBL6844786 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1GSK3B | |
| SCHEMBL839165 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK1ENPP1SMN1; SMN2 | |
| SCHEMBL24846407 | 0.74 | ENPP1 (1.00) | ENPP1TDP1L3MBTL1 | |
| SCHEMBL24847225 | 0.74 | ENPP1 (0.83) | MAPTENPP1TDP1L3MBTL1 | |
| SCHEMBL838331 | 0.73 | ALDH1A1 (0.66) | ALDH1A1MAPTMAPK1SMN1; SMN2HTT | |
| SCHEMBL24846414 | 0.73 | TDP1 (0.57) | ALDH1A1MAPTENPP1SMN1; SMN2HTT | |
| SCHEMBL24846438 | 0.72 | ENPP1 (0.79) | MAPTENPP1TDP1L3MBTL1 | |
| SCHEMBL24846440 | 0.72 | ENPP1 (0.68) | ALDH1A1MAPTENPP1SMN1; SMN2HTT | |
| SCHEMBL24846238 | 0.71 | ENPP1 (0.77) | MAPTENPP1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ATEN PORUS LIFESCIENCES PVT. LTD. (IN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ENPP1, ENPP3, PNP | ALDH1A1 3259/4885MAPT 2774/4885MAPK1 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.