Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526265 | 0.83 | L3MBTL1 (0.43) | CNR2TSHRKMT2ACNR1MTNR1A | |
| SCHEMBL25123251 | 0.83 | CNR2 (0.42) | CNR2TSHRNPC1ALDH1A1MEN1 | |
| SCHEMBL26224372 | 0.78 | TSHR (0.38) | CNR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22526269 | 0.78 | FOS (0.40) | CNR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22527268 | 0.75 | CNR2 (0.46) | CNR2TSHRCNR1 | |
| SCHEMBL9159855 | 0.75 | NQO1 (0.45) | TSHRNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL23189235 | 0.74 | IAPP (0.39) | ALDH1A1KDM4ECYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL14183051 | 0.74 | NQO1 (0.52) | TSHRNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL14583346 | 0.73 | CNR2 (0.50) | CNR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL24029703 | 0.72 | FOS (0.41) | CNR2NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |