SCHEMBL24848565

SCHEMBL24848565

Cc1nc(C)n2c1c1ccccc1n1c3ccccc3nc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
KDM4E B2RXH2 5/20 0.53
POLB P06746 4/20 0.53
HSD17B10 Q99714 3/20 0.53
LMNA P02545 2/20 0.53
TP53 P04637 1/20 0.53
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
GAA P10253 1/20 0.49
ALDH1A1 P00352 5/20 0.41
HPGD P15428 5/20 0.41
TSHR P16473 1/20 0.41
PDE10A Q9Y233 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
ADORA1 P30542 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
AGER Q15109 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24848558 0.80 KDM4E (0.46) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL17466962 0.77 MAPT (0.53) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL24848571 0.76 KDM4E (0.49) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL21065258 0.76 KMT2A (0.58) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL20547116 0.76 KDM4E (0.44) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL14868036 0.74 KDM4E (0.42) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL25636978 0.74 KDM4E (0.42) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL861183 0.74 KDM4E (0.57) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL24848568 0.73 KDM4E (0.57) MAPTKDM4EPOLBHSD17B10LMNA
SCHEMBL24495866 0.73 KDM4E (0.41) MAPTKDM4EPOLBHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230006153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC MAPT 1102/4885KDM4E 1544/4885POLB 1878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.