Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861183 | 0.80 | KDM4E (0.57) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL24848571 | 0.76 | KDM4E (0.49) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL24848565 | 0.76 | MAPT (0.53) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL21065259 | 0.75 | PDE10A (0.50) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL24848558 | 0.74 | KDM4E (0.46) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL24390087 | 0.73 | KDM4E (0.49) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL7340914 | 0.73 | TYMS (0.68) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL17993463 | 0.73 | KDM4E (0.65) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL20547116 | 0.72 | KDM4E (0.44) | KMT2APOLBMEN1HSD17B10HPGD | |
| SCHEMBL12797310 | 0.72 | POLB (0.50) | KMT2APOLBMEN1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399922-B1 | Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof | UNIVERSAL DISPLAY CORP (US) | 2019-06-26 | — | — | EP | claimed |
| EP-2399922-B1 | Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof | UNIVERSAL DISPLAY CORP (US) | 2019-06-26 | — | — | EP | disclosed |