SCHEMBL2654989

SCHEMBL2654989

CCCC(=O)OC(=O)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ALDH1A1 P00352 4/20 0.47
KMT2A Q03164 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
F2R P25116 1/20 0.44
MEN1 O00255 3/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPK1 P28482 2/20 0.43
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
GAA P10253 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7257515 0.89 ALDH1A1 (0.55) TSHRALDH1A1KMT2AMEN1MAPK1
SCHEMBL8948919 0.87 TSHR (0.52) TSHRALDH1A1KMT2ASMN1; SMN2MEN1
SCHEMBL28547230 0.85 TSHR (0.70) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL24848615 0.83 TSHR (0.53) TSHRALDH1A1KMT2ASMN1; SMN2F2R
SCHEMBL5663070 0.83 TSHR (0.55) TSHRALDH1A1KMT2ASMN1; SMN2NPC1
SCHEMBL28990208 0.83 ALDH1A1 (0.50) TSHRALDH1A1KMT2ASMN1; SMN2MAPK1
SCHEMBL27469326 0.83 KDM4E (0.50) TSHRALDH1A1KMT2AMEN1MAPK1
SCHEMBL10539582 0.81 SMN1; SMN2 (0.47) TSHRALDH1A1SMN1; SMN2F2RESR1
SCHEMBL2200203 0.81 ALDH1A1 (0.50) TSHRALDH1A1KMT2ASMN1; SMN2F2R
SCHEMBL29014554 0.81 F2R (0.46) TSHRALDH1A1KMT2ASMN1; SMN2F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778133-B high-pH chrome tanning auxiliary agent containing multifunctional structure, and preparation method and application thereof 南京工业大学 2023-06-16 CN disclosed
US-20230118444-A1 INFRARED-ABSORBING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND INFRARED SENSOR FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed
WO-2021256116-A1 INFRARED-ABSORBING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND INFRARED SENSOR 富士フイルム株式会社 2021-12-23 WO disclosed
CN-111240156-A Photosensitive resin composition, method for producing patterned cured film, and patterned cured film 东京应化工业株式会社 2020-06-05 CN disclosed
EP-1948614-A2 GLUCOKINASE ACTIVATORS Takeda San Diego, Inc. (US) 2008-07-30 EP disclosed
WO-2007061923-A2 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. (US) 2007-05-31 WO disclosed
US-4020073-A Process for O-acylating thallus salts of 2-pyridone TAYLOR EDWARD C 1977-04-26 US disclosed