SCHEMBL24848873

SCHEMBL24848873

N#Cc1ccc(COc2cccc(N[C@@H]3CCNC3)n2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 10/20 0.47
NRAS P01111 6/20 0.47
IRAK4 Q9NWZ3 6/20 0.46
IRAK1 P51617 4/20 0.45
PRKCI P41743 1/20 0.39
PDGFRB P09619 1/20 0.38
CDK7 P50613 1/20 0.38
CCNH P51946 1/20 0.38
HRH4 Q9H3N8 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
HRH2 P25021 1/20 0.38
CHEK2 O96017 1/20 0.38
ABL1 P00519 1/20 0.38
PDGFRA P16234 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
DDR1 Q08345 1/20 0.38
NTRK3 Q16288 1/20 0.38
AURKB Q96GD4 1/20 0.38
PDPK1 O15530 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30176835 1.00 FLT3 (0.47) FLT3NRASIRAK4IRAK1PRKCI
SCHEMBL24848620 0.94 IRAK4 (0.51) FLT3NRASIRAK4IRAK1PDGFRB
SCHEMBL23383280 0.85 FLT3 (0.51) FLT3NRASIRAK4IRAK1PDGFRB
SCHEMBL23383282 0.84 IRAK4 (0.43) FLT3IRAK4IRAK1PDGFRBCDK7
SCHEMBL23383546 0.81 FLT3 (0.43) FLT3NRASIRAK4IRAK1
SCHEMBL30176831 0.81 FLT3 (0.43) FLT3NRASIRAK4IRAK1
SCHEMBL24848634 0.81 FLT3 (0.43) FLT3NRASIRAK4IRAK1
SCHEMBL23383542 0.81 FLT3 (0.43) FLT3NRASIRAK4IRAK1
SCHEMBL23383324 0.79 IRAK4 (0.49) FLT3NRASIRAK4IRAK1PDGFRB
Trifluoroacetic Acid SCHEMBL29928889 0.78 HRH4 (0.49) FLT3NRASIRAK4IRAK1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002348-A1 GLP-1 Receptor Agonist and Use Thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002348-A1 GLP-1 Receptor Agonist and Use Thereof GLP1R, GIPR, GPR119 FLT3 2309/4885NRAS 2518/4885IRAK4 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.