Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 10/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.44 |
| ▸ | NRAS | P01111 | 6/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 4/20 | 0.44 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | CDK7 | P50613 | 3/20 | 0.39 |
| ▸ | CCNH | P51946 | 3/20 | 0.39 |
| ▸ | BLK | P51451 | 2/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29695902 | 0.95 | HRH4 (0.47) | HRH4HRH3FLT3IRAK4NRAS | |
| SCHEMBL23383280 | 0.91 | FLT3 (0.51) | FLT3IRAK4NRASIRAK1LCK | |
| SCHEMBL23383324 | 0.85 | IRAK4 (0.49) | HRH3FLT3IRAK4NRASIRAK1 | |
| Trifluoroacetic Acid SCHEMBL29586524 | 0.84 | HRH4 (0.49) | HRH4HRH3FLT3IRAK4NRAS | |
| Trifluoroacetic Acid SCHEMBL29928577 | 0.82 | HRH4 (0.41) | HRH4HRH3FLT3CHEK1 | |
| Trifluoroacetic Acid SCHEMBL25272721 | 0.81 | GLP1R (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL30404349 | 0.81 | GLP1R (0.42) | — | |
| SCHEMBL24848873 | 0.78 | FLT3 (0.47) | HRH4HRH3FLT3IRAK4NRAS | |
| SCHEMBL30176835 | 0.78 | FLT3 (0.47) | HRH4HRH3FLT3IRAK4NRAS | |
| Trifluoroacetic Acid SCHEMBL29928598 | 0.77 | F10 (0.43) | HRH4HRH3FLT3CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059929-A1 | GLP-1 RECEPTOR AGONIST AND USE THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2022-09-21 | — | — | EP | disclosed |