SCHEMBL24849007

SCHEMBL24849007

c1ccc2c(c1)ccc1c3ccccc3n(-c3nc4ccccc4nc3-c3ccc4oc5ccc6oc7ccccc7c6c5c4c3)c21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
SIRT2 Q8IXJ6 3/20 0.32
SIRT1 Q96EB6 3/20 0.32
CHEK2 O96017 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18926294 0.90 TUBB4A (0.34) TDP1L3MBTL1NPC1RAB9A
SCHEMBL24848686 0.89 SIRT2 (0.33) TDP1L3MBTL1SIRT2SIRT1CHEK2
SCHEMBL24275442 0.87 TDP1 (0.33) TDP1L3MBTL1NPC1RAB9AKDM4E
SCHEMBL21716993 0.85 CHEK2 (0.33) SIRT2SIRT1CHEK2
SCHEMBL18926305 0.84 HSD17B10 (0.39) TDP1L3MBTL1NPC1RAB9AKDM4E
SCHEMBL23471675 0.84 SIRT2 (0.30) SIRT2SIRT1CHEK2
SCHEMBL24104889 0.84 TUBB4A (0.40) KDM4EMAPTHPGD
SCHEMBL21716278 0.83 GSR (0.35) SIRT2SIRT1CHEK2
SCHEMBL19543859 0.83 CHEK2 (0.33) TDP1L3MBTL1SIRT2SIRT1CHEK2
SCHEMBL21213761 0.82 HCRTR1 (0.33) SIRT2SIRT1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed