SCHEMBL24848686

SCHEMBL24848686

c1ccc2c(c1)ccc1c3ccccc3n(-c3nc4ccccc4nc3-c3ccc4oc5c(ccc6c7ccccc7oc65)c4c3)c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 5/20 0.33
SIRT1 Q96EB6 5/20 0.33
CHEK2 O96017 1/20 0.32
KDM4E B2RXH2 6/20 0.32
MAPT P10636 4/20 0.32
HPGD P15428 3/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
GLA P06280 2/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 5/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HNF4A P41235 1/20 0.31
NISCH Q9Y2I1 1/20 0.30
GAA P10253 2/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849007 0.89 TDP1 (0.33) SIRT2SIRT1CHEK2KDM4EMAPT
SCHEMBL24104884 0.85 PRKDC (0.35) SIRT2SIRT1KDM4EMAPTHPGD
SCHEMBL19543859 0.84 CHEK2 (0.33) SIRT2SIRT1CHEK2KDM4EMAPT
SCHEMBL21716278 0.84 GSR (0.35) SIRT2SIRT1CHEK2
SCHEMBL21716993 0.84 CHEK2 (0.33) SIRT2SIRT1CHEK2
SCHEMBL24275442 0.84 TDP1 (0.33) KDM4EMAPTHPGDHTTTDP1
SCHEMBL19655164 0.84 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EMAPT
SCHEMBL23471675 0.83 SIRT2 (0.30) SIRT2SIRT1CHEK2
SCHEMBL18926294 0.83 TUBB4A (0.34) TDP1L3MBTL1
SCHEMBL24104889 0.83 TUBB4A (0.40) KDM4EMAPTHPGDALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed