⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22971697 | 0.90 | ALDH1A1 (0.31) | — | |
| SCHEMBL29332959 | 0.85 | ALDH1A1 (0.31) | — | |
| SCHEMBL22374290 | 0.83 | ESR1 (0.31) | — | |
| SCHEMBL22333290 | 0.81 | — | — | |
| SCHEMBL19308850 | 0.76 | RXRA (0.31) | — | |
| SCHEMBL22222009 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL18812112 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL20666526 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL23661740 | 0.72 | ESR1 (0.37) | — | |
| SCHEMBL21653572 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20230000843-A1 | MEDICINAL COGNITIVE TREATMENTS | Actinogen Medical Limited (AU) | 2023-01-05 | — | — | US | disclosed |