SCHEMBL24849445

SCHEMBL24849445

Clc1cccc2c1sc1ccc3c4ccccc4sc3c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.45
ALOX5 P09917 1/20 0.40
MAPT P10636 4/20 0.39
RAB9A P51151 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
PARP14 Q460N5 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 2/20 0.37
MCL1 Q07820 2/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
HCRTR1 O43613 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30120535 0.91 GPR3 (0.54) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL20690712 0.91 GPR3 (0.54) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL21616197 0.83 CYP1A2 (0.52) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL24889877 0.83 CYP1A2 (0.42) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL1636532 0.83 GPR3 (0.61) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL22129989 0.82 PARP14 (0.50) GPR3ALOX5MAPTRAB9APARP14
SCHEMBL20041175 0.81 ALOX5 (0.47) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL22129988 0.81 GPR3 (0.43) GPR3ALOX5MAPTRAB9AALDH1A1
SCHEMBL23981335 0.79 CYP1A2 (0.50) RAB9AALDH1A1HPGDCYP1A2CYP2A6
SCHEMBL24787556 0.78 ALOX5 (0.40) GPR3ALOX5MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed