SCHEMBL24849873

SCHEMBL24849873

C/C=C\C(=N/C)c1ccc(F)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
PLA2G7 Q13093 2/20 0.40
RAB9A P51151 2/20 0.39
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CHRNA1 P02708 1/20 0.34
CHRNG P07510 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
SLC6A2 P23975 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CHRND Q07001 1/20 0.34
PTGS2 P35354 2/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20387299 0.73 ALDH1A1 (0.43) CES2CES1RAB9AKMT2AMEN1
SCHEMBL21497370 0.71 CES2 (0.39) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL20247782 0.69 CES2 (0.32) CES2CES1RAB9AKMT2APTGS2
SCHEMBL4790688 0.69 CES2 (0.52) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL6921313 0.69 CES2 (0.52) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL2096114 0.69 CES2 (0.52) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL23958880 0.67 CES2 (0.45) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL23905448 0.66 CES2 (0.44) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL16954373 0.65 CES2 (0.58) CES2CES1PLA2G7RAB9AKMT2A
SCHEMBL6990311 0.65 CES2 (0.64) CES2CES1PLA2G7RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277015-A1 HETEROCYCLIC COMPOUND AND RESISTANT HARMFUL ARTHROPOD-CONTROLLING METHOD FOR COMPOSITION CONTAINING SAME 住友化学株式会社 2023-01-05 WO disclosed