Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 10/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19226031 | 0.90 | NPC1 (0.63) | ABL1RAB9ATP53NPC1KCNK3 | |
| SCHEMBL23091776 | 0.85 | ABL1 (0.65) | ABL1KCNH2MEN1KMT2AHTT | |
| SCHEMBL29832702 | 0.84 | ABL1 (0.62) | ABL1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4248125 | 0.81 | KCNK3 (0.82) | RAB9ATP53NPC1KCNK3KCNK9 | |
| SCHEMBL19545229 | 0.80 | ABL1 (0.54) | ABL1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16714125 | 0.79 | ABL1 (1.00) | ABL1 | |
| SCHEMBL4257440 | 0.79 | NPC1 (0.81) | RAB9ATP53NPC1KCNK3KCNK9 | |
| SCHEMBL30048093 | 0.79 | NPC1 (0.81) | RAB9ATP53NPC1KCNK3KCNK9 | |
| SCHEMBL30739887 | 0.78 | MEN1 (0.78) | RAB9ATP53NPC1KCNK3KCNK9 | |
| SCHEMBL4248711 | 0.78 | KCNK3 (0.81) | RAB9ATP53NPC1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | ABL2, ABL1, ALK | ABL1 2/4885RAB9A 1661/4885TP53 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.