Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 6/20 | 0.78 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30048093 | 0.88 | NPC1 (0.81) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL4257440 | 0.88 | NPC1 (0.81) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL4247170 | 0.86 | KCNK3 (0.91) | KCNK3KMT2AMEN1TP53NPC1 | |
| SCHEMBL30555199 | 0.85 | TP53 (1.00) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL5380687 | 0.85 | TP53 (1.00) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL3674558 | 0.85 | KCNK3 (0.71) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL30608967 | 0.85 | KCNK3 (0.87) | KCNK3KMT2AMEN1TP53NPC1 | |
| SCHEMBL259666 | 0.85 | KCNK3 (0.87) | KCNK3KMT2AMEN1TP53NPC1 | |
| SCHEMBL27998568 | 0.85 | KMT2A (0.59) | KCNK3KMT2AMEN1TP53KDM4E | |
| SCHEMBL16675166 | 0.84 | KCNK3 (0.89) | KCNK3KMT2AMEN1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102525-B | Benzamide derivatives and uses thereof | 沈阳药科大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-116102525-A | Benzamide derivatives and uses thereof | 沈阳药科大学 | 2023-05-12 | — | — | CN | disclosed |
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| CN-107652200-B | A method of N- aryl Zhong Fang amide is synthesized using aryl hydrazine | 陕西科技大学 | 2019-06-14 | — | — | CN | disclosed |
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | GABBR1, GABBR2, CHRM2 | KCNK3 1019/4885KMT2A 632/4885MEN1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.