Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479429 | 0.91 | NPC1 (0.60) | MAP3K5RAB9ANPC1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL2482555 | 0.91 | MAP3K5 (0.61) | MAP3K5RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL12199516 | 0.90 | MAP3K5 (0.68) | MAP3K5RAB9ANPC1KMT2AKDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL403207 | 0.88 | SCD (0.67) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2485817 | 0.83 | SMN1; SMN2 (0.60) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2482852 | 0.82 | SCD (0.66) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5713530 | 0.81 | MAP3K5 (0.75) | MAP3K5RAB9ANPC1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL2483587 | 0.79 | SCD (0.70) | RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13329390 | 0.78 | MAP3K5 (0.83) | MAP3K5RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL2483973 | 0.78 | MAPT (0.59) | RAB9ANPC1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376463-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |