Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852549 | 1.00 | IL4I1 (0.52) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24852748 | 1.00 | IL4I1 (0.52) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24851945 | 0.90 | IL4I1 (0.56) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24852579 | 0.81 | IL4I1 (0.51) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24852168 | 0.78 | IL4I1 (0.54) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24852066 | 0.78 | IL4I1 (0.56) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL30162602 | 0.77 | IL4I1 (0.54) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24852634 | 0.77 | IL4I1 (0.54) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24851942 | 0.75 | IL4I1 (0.50) | IL4I1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL24851784 | 0.74 | IL4I1 (0.60) | IL4I1ALDH1A1TSHRKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |