Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24853031 | 1.00 | IL4I1 (0.78) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852529 | 1.00 | IL4I1 (0.78) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852527 | 0.88 | IL4I1 (1.00) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24853032 | 0.86 | IL4I1 (0.91) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24851965 | 0.86 | IL4I1 (0.83) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852038 | 0.85 | IL4I1 (0.81) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852524 | 0.83 | IL4I1 (0.85) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL3717832 | 0.75 | IL4I1 (0.66) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852647 | 0.73 | IL4I1 (0.63) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24852649 | 0.73 | IL4I1 (0.63) | IL4I1ALDH1A1KDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |