Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.66 |
| ▸ | IDH1 | O75874 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852055 | 0.85 | CYP19A1 (0.52) | IL4I1IDH1MAPK1 | |
| SCHEMBL6196432 | 0.82 | IL4I1 (0.47) | IL4I1IDH1CYP11B1CYP11B2PDE3B | |
| SCHEMBL6843410 | 0.82 | IL4I1 (0.47) | IL4I1IDH1CYP11B1CYP11B2PDE3B | |
| SCHEMBL24852522 | 0.82 | IL4I1 (0.61) | IL4I1IDH1KDM4EALDH1A1HPGD | |
| SCHEMBL24851784 | 0.81 | IL4I1 (0.60) | IL4I1KDM4EALDH1A1HPGDPDE3B | |
| SCHEMBL24852035 | 0.80 | ALDH1A1 (0.56) | IL4I1IDH1KDM4EALDH1A1HPGD | |
| SCHEMBL24852527 | 0.80 | IL4I1 (1.00) | IL4I1IDH1KDM4EALDH1A1HPGD | |
| SCHEMBL6991388 | 0.80 | LOXL2 (0.49) | IL4I1CYP11B1CYP11B2 | |
| SCHEMBL24852525 | 0.79 | IL4I1 (0.57) | IL4I1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24851965 | 0.78 | IL4I1 (0.83) | IL4I1IDH1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |