Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24001754 | 1.00 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24013931 | 1.00 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19996061 | 0.91 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20751433 | 0.91 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9808661 | 0.91 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27004508 | 0.91 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26522108 | 0.90 | — | — | |
| SCHEMBL21698637 | 0.88 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17255235 | 0.84 | NFKB1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL466814 | 0.83 | PAOX (0.46) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091565-A1 | NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023275394-A1 | ANTI-PROTAC ANTIBODIES AND COMPLEXES | MERCK PATENT GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |