Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.47 |
| ▸ | KIT | P10721 | 7/20 | 0.47 |
| ▸ | FLT3 | P36888 | 7/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.45 |
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | CSF1R | P07333 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | PRKACA | P17612 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.45 |
| ▸ | MARK3 | P27448 | 3/20 | 0.45 |
| ▸ | MARK2 | Q7KZI7 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788040 | 1.00 | PDPK1 (0.53) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL13236555 | 0.86 | PDPK1 (0.56) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL30168107 | 0.84 | KDR (0.48) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL24852599 | 0.84 | KDR (0.48) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL2660889 | 0.79 | GAA (0.56) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL10368038 | 0.73 | PDPK1 (0.61) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL569660 | 0.73 | GAA (0.61) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL20571471 | 0.72 | GAA (0.56) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL628649 | 0.72 | PDPK1 (0.66) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL30065304 | 0.72 | PDPK1 (0.66) | PDPK1GAAMAP2K1KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2024-11-21 | — | — | US | disclosed |
| CN-117580569-A | Heterocyclic aldehyde capture compounds and uses thereof | 奥尔德拉医疗公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023278816-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDH1A2, ALDH2, SSB | PDPK1 3263/4885GAA 506/4885MAP2K1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.