Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854521 | 0.87 | HPGD (0.33) | HPGDHSP90AA1HSP90AB1ESR1HTR2C | |
| SCHEMBL23370304 | 0.85 | CYP1A2 (0.33) | HSP90AA1HSP90AB1ESR1 | |
| SCHEMBL29814445 | 0.85 | CYP1A2 (0.33) | HSP90AA1HSP90AB1ESR1 | |
| SCHEMBL23370320 | 0.83 | PPARG (0.36) | LTA4HKCNH2HPGDPPARGHSP90AA1 | |
| SCHEMBL24853719 | 0.82 | ESR1 (0.32) | HSP90AA1HSP90AB1ESR1 | |
| SCHEMBL24854239 | 0.82 | CYP1A2 (0.33) | HSP90AA1HSP90AB1ESR1 | |
| SCHEMBL24854048 | 0.81 | LTA4H (0.36) | LTA4HKCNH2PPARGBACE1 | |
| SCHEMBL24853571 | 0.81 | HSP90AA1 (0.35) | HPGDHSP90AA1HSP90AB1ESR1 | |
| SCHEMBL23370310 | 0.81 | HPGD (0.32) | HPGD | |
| SCHEMBL24854536 | 0.79 | BUB1 (0.35) | HPGDHSP90AA1HSP90AB1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | AZI2, PDXK, DPYD | LTA4H 4134/4885KCNH2 250/4885HPGD 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.