Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | LITAF | Q99732 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854520 | 0.99 | ESR1 (0.38) | ESR1MPOSLC9A1CYP1A2CYP3A4 | |
| SCHEMBL24854022 | 0.91 | ESR1 (0.39) | ESR1MPOCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24853567 | 0.88 | CYP1A2 (0.32) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL24854032 | 0.87 | CYP1A2 (0.34) | ESR1MPOCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24853761 | 0.85 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL24854239 | 0.85 | CYP1A2 (0.33) | ESR1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24854064 | 0.84 | MPO (0.37) | MPOCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24853776 | 0.83 | CYP1A2 (0.31) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL23370304 | 0.83 | CYP1A2 (0.33) | ESR1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24853772 | 0.83 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | AZI2, PDXK, DPYD | ESR1 4145/4885MPO 2481/4885SLC9A1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.