SCHEMBL248540

SCHEMBL248540

CC1(C(=O)O)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487839 1.00
Hydrochloric Acid SCHEMBL9313203 0.97 FFAR3 (0.39)
SCHEMBL9312275 0.79 PKM (0.31)
SCHEMBL8523316 0.78
SCHEMBL8611547 0.78
SCHEMBL8523602 0.78
SCHEMBL19307390 0.78 FFAR3 (0.47)
SCHEMBL301061 0.78 FFAR3 (0.47)
SCHEMBL9592172 0.78 FFAR3 (0.33)
SCHEMBL9577996 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5095147-A Intermediates for fungicides BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US claimed
JP-2088535-A None JP disclosed
EP-4747258-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics, Inc. (US) 2026-05-27 EP disclosed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed
US-20250376482-A1 TRICYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2025-12-11 US disclosed
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 US disclosed
US-20250243177-A1 sGC STIMULATORS CYCLERION THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12338241-B2 Bicyclic sulfones and sulfoxides and methods of use thereof GENENTECH, INC. (US) 2025-06-24 US disclosed
EP-4562001-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS Nura Bio, Inc. (US) 2025-06-04 EP disclosed
EP-0351647-B1 2,2-DIFLUOROCYCLOPROPYL DERIVATES BAYER AG (DE) 1992-12-30 EP disclosed
US-5126338-A FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US disclosed
US-5097050-A Intermediates for synthesis of fungicidal hydroxyalkinyl-azoles BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
US-5095147-A Intermediates for fungicides BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
US-5047415-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0436348-A2 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LIMITED (GB) 1991-07-10 EP disclosed
US-5025030-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-06-18 US disclosed
JP-H0288535-A 2,2-DIFLUOROCYCLOPROPYL DERIVATIVE BAYER AG 1990-03-28 JP disclosed
EP-0351646-A2 Hydroxyalkinyl-azolyl derivatives BAYER AG (DE) 1990-01-24 EP disclosed
EP-0351647-A2 2,2-Difluorocyclopropyl derivates BAYER AG (DE) 1990-01-24 EP disclosed