SCHEMBL9577996

SCHEMBL9577996

CC(=O)C1(C)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312275 0.79 PKM (0.31)
SCHEMBL248540 0.77
SCHEMBL31487839 0.77
SCHEMBL5523402 0.75
SCHEMBL231482 0.74
Hydrochloric Acid SCHEMBL9313203 0.74 FFAR3 (0.39)
SCHEMBL9577974 0.74
SCHEMBL24261137 0.71
SCHEMBL17468795 0.71
SCHEMBL9577989 0.70 TRPA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264632-A Fungicide intermediate BAYER AKTIENGESELLSCHAFT (DE) 1993-11-23 US claimed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
EP-3019196-B1 COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-06 EP disclosed
EP-2802326-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-04-18 EP disclosed
US-9770439-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-26 US disclosed
US-20160199355-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL MAYERS SQUIBB COMPANY (US) 2016-07-14 US disclosed
US-20160158200-A1 Combinations of Hepatitis C Virus Inhibitors BRISTOL MYERS SQUIBB CO (US) 2016-06-09 US disclosed
US-9326973-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-05-03 US disclosed
US-20150297568-A1 Hepatitis C Virus Inhibitors BRISTOL MYERS SQUIBB CO (US) 2015-10-22 US disclosed
US-20150023913-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2015-01-22 US disclosed
US-20130183269-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-07-18 US disclosed
US-5264632-A Fungicide intermediate BAYER AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed
US-5208388-A Chemical intermediates for heterocyclic fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
EP-0351647-B1 2,2-DIFLUOROCYCLOPROPYL DERIVATES BAYER AG (DE) 1992-12-30 EP disclosed
US-5095147-A Intermediates for fungicides BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
US-5047415-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0351649-A2 2,2-Dihalocyclopropyl-hydroxy-ethyl triazoles BAYER AG (DE) 1990-01-24 EP disclosed
EP-0351647-A2 2,2-Difluorocyclopropyl derivates BAYER AG (DE) 1990-01-24 EP disclosed