Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844606 | 1.00 | HTR6 (0.41) | HTR6KCNQ3KCNQ2ALDH1A1KDM4E | |
| SCHEMBL4376044 | 0.87 | ALDH1A1 (0.48) | HTR6ALDH1A1MEN1KMT2AACHE | |
| SCHEMBL29443995 | 0.87 | ALDH1A1 (0.48) | HTR6ALDH1A1MEN1KMT2AACHE | |
| SCHEMBL16729466 | 0.83 | MAP2K4 (0.44) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2461044 | 0.83 | ALDH1A1 (0.55) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15902182 | 0.83 | HTR6 (0.46) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29443980 | 0.83 | HTR6 (0.46) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7715925 | 0.81 | HTR6 (0.44) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2454469 | 0.81 | HTR6 (0.44) | HTR6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17968965 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EMEN1KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616010-A | Process for preparing (S) -2- (4-chloro-2-methoxyphenyl) -2- ((3-methoxy-5- (methylsulfonyl) phenyl) amino) -1- (1H-indol-3-yl) ketene derivatives | 杨森制药公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023274237-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3-METHOXY-5-(METHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES | Janssen Pharmaceuticals, Inc. (US) | 2023-01-05 | — | — | WO | disclosed |