Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366961 | 0.86 | EGFR (0.40) | EGFRHTR2AHTR2C | |
| SCHEMBL24855371 | 0.77 | — | — | |
| SCHEMBL29326257 | 0.76 | EGFR (0.33) | EGFRHTR2AHTR2C | |
| SCHEMBL23772414 | 0.72 | EGFR (0.45) | EGFRHTR2AHTR2C | |
| SCHEMBL24925867 | 0.71 | — | — | |
| SCHEMBL29556343 | 0.71 | LPL (0.35) | — | |
| SCHEMBL16035665 | 0.71 | LPL (0.35) | — | |
| SCHEMBL24855708 | 0.71 | QDPR (0.34) | EGFR | |
| SCHEMBL30593118 | 0.70 | EGFR (0.34) | EGFR | |
| SCHEMBL26608347 | 0.70 | EGFR (0.34) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275366-A1 | NLRP3 INFLAMMASOME INHIBITORS | ASTRAZENECA AB (SE) | 2023-01-05 | — | — | WO | disclosed |