SCHEMBL24855822

SCHEMBL24855822

c1ccc(-c2cccc(-c3nc(-c4cccc(-c5cccc6oc7ccccc7c56)c4)nc(-n4c5ccccc5c5cccc(-c6ccccc6)c54)n3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
DUSP3 P51452 1/20 0.32
PRKDC P78527 2/20 0.32
PLA2G10 O15496 1/20 0.31
TERT O14746 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24855957 0.97 BACE1 (0.34) BACE1DUSP3TERTMAPT
SCHEMBL24855840 0.94 BACE1 (0.32) BACE1PLA2G2APLA2G4ADUSP3PRKDC
SCHEMBL24882810 0.94 BACE1 (0.32) BACE1PLA2G2APLA2G4ADUSP3PRKDC
SCHEMBL24883161 0.94 PLA2G2A (0.35) BACE1PLA2G2APLA2G4ADUSP3PRKDC
SCHEMBL24855821 0.93 PLA2G2A (0.35) BACE1PLA2G2APLA2G4APRKDCPLA2G10
SCHEMBL24855847 0.92 DUSP3 (0.34) DUSP3MAPT
SCHEMBL24855834 0.92 MAPT (0.30) BACE1DUSP3MAPT
SCHEMBL24883070 0.92 BACE1 (0.33) BACE1DUSP3PRKDCMAPT
SCHEMBL24882880 0.92 PLA2G2A (0.33) BACE1PLA2G2APLA2G4ADUSP3PLA2G10
SCHEMBL22845395 0.91 PLA2G2A (0.36) BACE1PLA2G2APLA2G4APRKDCPLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023273356-A1 COMPOUND CONTAINING CARBAZOLE AND CARBAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE 南京高光半导体材料有限公司 2023-01-05 WO disclosed