SCHEMBL24855834

SCHEMBL24855834

c1ccc(-c2cc(-c3cccc(-c4nc(-c5ccccc5)nc(-n5c6ccccc6c6cccc(-c7ccccc7)c65)n4)c3)c3c(c2)oc2ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.30
BACE1 P56817 1/20 0.30
ALDH1A1 P00352 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
DUSP3 P51452 1/20 0.30
KDM4E B2RXH2 2/20 0.30
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24882820 0.95 BACE1 (0.33) MAPTBACE1ALDH1A1NPSR1DUSP3
SCHEMBL24701827 0.95 MAPT (0.32) MAPTBACE1ALDH1A1NPSR1DUSP3
SCHEMBL24882803 0.95 MAPT (0.32) MAPTBACE1ALDH1A1NPSR1DUSP3
SCHEMBL24855962 0.93 TSHR (0.32) MAPTALDH1A1NPSR1RXFP1KDM4E
SCHEMBL24855957 0.93 BACE1 (0.34) MAPTBACE1ALDH1A1NPSR1RXFP1
SCHEMBL24855822 0.92 BACE1 (0.34) MAPTBACE1DUSP3
SCHEMBL24855964 0.92 PLA2G2A (0.33) MAPTBACE1ALDH1A1NPSR1RXFP1
SCHEMBL24855965 0.91 BACE1 (0.31) BACE1
SCHEMBL22845371 0.91 PLA2G2A (0.34) MAPTTSHRLMNAPOLB
SCHEMBL24855955 0.91 PLA2G2A (0.33) ALDH1A1NPSR1RXFP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023273356-A1 COMPOUND CONTAINING CARBAZOLE AND CARBAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE 南京高光半导体材料有限公司 2023-01-05 WO disclosed