SCHEMBL2485698

SCHEMBL2485698

CC(F)=C(F)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
GAA P10253 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 2/20 0.46
SMN1; SMN2 Q16637 4/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 3/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ACHE P22303 1/20 0.39
PTPN1 P18031 1/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
ELANE P08246 1/20 0.38
TP53 P04637 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970209 0.80 CES2 (0.54) CES2CES1GAAALDH1A1ALOX15
SCHEMBL29056464 0.77 ALDH1A1 (0.54) CES2CES1GAAALDH1A1ALOX15
SCHEMBL14127160 0.77 CES2 (0.56) CES2CES1GAAALDH1A1ALOX15
SCHEMBL1433491 0.76 CES2 (0.50) CES2CES1GAAALDH1A1ALOX15
SCHEMBL6549015 0.75 CES2 (0.54) CES2CES1GAAALDH1A1ALOX15
SCHEMBL30317882 0.74 CES2 (0.48) CES2CES1GAAALDH1A1ALOX15
SCHEMBL8821193 0.74 CES2 (0.48) CES2CES1GAAALDH1A1ALOX15
SCHEMBL489916 0.74 CES2 (0.59) CES2CES1GAAALDH1A1ALOX15
SCHEMBL23429108 0.73 CES2 (0.52) CES2CES1GAAALDH1A1ALOX15
SCHEMBL13461 0.73 CES2 (0.65) CES2CES1GAAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1410109-B1 PHOTOSENSITIVE RESIN COMPOSITION BASF SE (DE) 2011-10-26 EP disclosed
US-7829257-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. (US) 2010-11-09 US disclosed
EP-1395615-B1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE BASF SE (DE) 2009-10-21 EP disclosed
US-7556843-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-07-07 US disclosed
US-7425585-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-16 US disclosed
US-7381842-B2 Oxime ester photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-06-03 US disclosed
US-20070259278-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-11-08 US disclosed
US-20070249748-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-10-25 US disclosed
US-7247659-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-24 US disclosed
US-7189489-B2 Oxime ester photoiniators having a combined structure CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-13 US disclosed
EP-0152425-A1 STABLE DISPERSIONS OF ORGANIC POLYMERS IN POLYEPOXIDES. DOW CHEMICAL CO (US) 1985-08-28 EP disclosed
WO-1985000610-A1 STABLE DISPERSIONS OF ORGANIC POLYMERS IN POLYEPOXIDES THE DOW CHEMICAL COMPANY (US) 1985-02-14 WO disclosed
US-4477525-A Graft polyesters and sized textiles BASF WYANDOTTE CORPORATION (US) 1984-10-16 US disclosed
US-4367308-A Cross-linked graft polyesters and sized textiles BASF WYANDOTTE CORPORATION (US) 1983-01-04 US disclosed
US-4275176-A Graft polyesters and sized textiles BASF WYANDOTTE CORPORATION (US) 1981-06-23 US disclosed
US-4263337-A Sizing textile with in situ graft polyester BASF WYANDOTTE CORPORATION (US) 1981-04-21 US disclosed
US-4259457-A Graft polyesters and sized textiles BASF WYANDOTTE CORPORATION (US) 1981-03-31 US disclosed
US-4225681-A Graft polyesters and sized textiles BASF WYANDOTTE CORPORATION (US) 1980-09-30 US disclosed
EP-0010582-A2 Graft polyester products, method of sizing yarns therewith and a synthetic fiber sized with such graft polyester products BASF WYANDOTTE CORPORATION (US) 1980-05-14 EP disclosed
US-3953393-A ALKYL MERCAPTAN CHAIN TRANSFERRING AGENT BASF WYANDOTTE CORPORATION (US) 1976-04-27 US disclosed