Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727709 | 0.84 | CSNK2A1 (0.35) | GRM4CSNK2A1RPS6KB1CSNK2A2CSNK2B | |
| SCHEMBL24857279 | 0.79 | RPS6KB1 (0.31) | RPS6KB1 | |
| SCHEMBL22317823 | 0.76 | CSNK2A1 (0.32) | CSNK2A1 | |
| SCHEMBL20399898 | 0.76 | RPS6KA5 (0.36) | CSNK2A1 | |
| SCHEMBL29421577 | 0.76 | CSNK2A1 (0.32) | CSNK2A1 | |
| SCHEMBL24857280 | 0.76 | RPS6KB1 (0.33) | RPS6KB1 | |
| SCHEMBL30573397 | 0.74 | CSNK2A1 (0.34) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL15741558 | 0.72 | RPS6KB1 (0.35) | GRM4CSNK2A1RPS6KB1CSNK2A2CSNK2B | |
| SCHEMBL30449241 | 0.72 | RPS6KB1 (0.35) | GRM4CSNK2A1RPS6KB1CSNK2A2CSNK2B | |
| SCHEMBL22220472 | 0.69 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274324-A9 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023134465-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023274324-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-01-05 | — | — | WO | disclosed |