Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24857419 | 0.80 | PDE10A (0.34) | PDE10AHAVCR2HSD17B10 | |
| SCHEMBL23029998 | 0.80 | PDE10A (0.34) | HTR6SMN1; SMN2PDE10AHAVCR2HSD17B10 | |
| SCHEMBL23029977 | 0.77 | HAVCR2 (0.35) | HTR6SMN1; SMN2PDE10AHAVCR2HSD17B10 | |
| SCHEMBL24857439 | 0.74 | PDE10A (0.34) | PDE10AHAVCR2HSD17B10 | |
| SCHEMBL24857426 | 0.72 | ENPP1 (0.38) | — | |
| SCHEMBL24858351 | 0.66 | ALOX15 (0.31) | — | |
| SCHEMBL24857423 | 0.65 | KDM4E (0.35) | SMN1; SMN2PDE10AHAVCR2HSD17B10 | |
| SCHEMBL24857436 | 0.59 | F2RL1 (0.31) | — | |
| SCHEMBL23029984 | 0.57 | PDE10A (0.36) | PDE10AHAVCR2HSD17B10 | |
| SCHEMBL23029831 | 0.56 | EGLN2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | EZH2, EED, SUZ12 | HTR6 2598/4885SMN1; SMN2 1471/4885PDE10A 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.