SCHEMBL248576

SCHEMBL248576

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675830 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL10397345 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL6742202 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL30607056 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL8699051 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL6846353 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL11693903 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL793254 0.96 LMNA (0.41) LMNATHRBCA2
SCHEMBL9580829 0.88 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL180330 0.87 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10543273-B2 Anti-fibroblastic fluorochemical emulsion therapies MCLEAY MATTHEW T (US) 2020-01-28 US claimed
CN-110465271-A A kind of synthetic method and application of temperature control targeted capture material SICHUAN UNIV OF SCIENCE & ENGINEERING CO LTD 2019-11-19 CN claimed
CN-107043620-B A kind of preparation method of liquid carbon dioxide thickening agent 西南石油大学 2019-10-15 CN claimed
CN-110028693-A A kind of preparation method of anti-odour absorption pipeline 杭州气味王国科技有限公司 2019-07-19 CN claimed
CN-109987578-A A method of constructing single concave inward structure on micro-column sublist face 电子科技大学 2019-07-09 CN claimed
US-20190201556-A1 FLUOROCHEMICAL TARGETED THERAPIES MT RESEARCH, LLC 2019-07-04 US claimed
CN-109881266-A A kind of fiber array controllable method for preparing based on super-double-hydrophobic surface 电子科技大学 2019-06-14 CN claimed
CN-109824937-A A kind of preparation method of imitative mushroom bar orientation oil absorption material 电子科技大学 2019-05-31 CN claimed
EP-3458037-A1 FLUOROCHEMICAL TARGETED THERAPIES MTM Research, LLC (US) 2019-03-27 EP claimed
CN-109468847-A A kind of super-amphiphobic textile finish and its preparation method and application 东南大学 2019-03-15 CN claimed
US-20050256211-A9 Patient oxygenation using stabilized fluorocarbon emulsions PFC THERAPEUTICS, LLC 2005-11-17 US claimed
CN-1687180-A Method for preparing super branched polyacrylate fluorine and application in finishing agent for textile YINGZHENG SCIRNCE AND TECHNOLO (CN) 2005-10-26 CN claimed
US-20040068020-A1 Patient oxygenation using stabilized fluorocarbon emulsions WEERS JEFFRY GREG (US) 2004-04-08 US claimed
EP-1208851-A2 A medicament for pulmonary drug delivery ALLIANCE PHARMACEUTICAL CORPORATION (US) 2002-05-29 EP claimed
EP-0831770-B1 CONTINUOUS FLUOROCHEMICAL MICRODISPERSIONS FOR THE DELIVERY OF PHARMACEUTICAL AGENTS ALLIANCE PHARMA (US) 2000-08-16 EP claimed
US-5874481-A Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents ALLIANCE PHARMACEUTICAL CORP. (US) 1999-02-23 US claimed
EP-0831770-A1 CONTINUOUS FLUOROCHEMICAL MICRODISPERSIONS FOR THE DELIVERY OF PHARMACEUTICAL AGENTS ALLIANCE PHARMACEUTICAL CORP. (US) 1998-04-01 EP claimed
US-5667809-A Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents ALLIANCE PHARMACEUTICAL CORP. (US) 1997-09-16 US claimed
WO-1996040052-A1 FLUOROCHEMICAL SOLUTIONS FOR THE DELIVERY OF LIPOPHILIC PHARMACEUTICAL AGENTS ALLIANCE PHARMACEUTICAL CORP. (US) 1996-12-19 WO claimed
WO-1996040053-A1 CONTINUOUS FLUOROCHEMICAL MICRODISPERSIONS FOR THE DELIVERY OF PHARMACEUTICAL AGENTS ALLIANCE PHARMACEUTICAL CORP. (US) 1996-12-19 WO claimed