SCHEMBL8675830

SCHEMBL8675830

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397345 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL6742202 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL30607056 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL248576 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL8699051 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL6846353 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL11693903 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL793254 0.96 LMNA (0.41) LMNATHRBCA2
SCHEMBL9580829 0.88 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL180330 0.87 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845620-B1 COMPOSITION FOR HEAT CYCLE SYSTEMS, AND HEAT CYCLE SYSTEM AGC INC (JP) 2024-09-18 EP disclosed
US-20220259474-A1 COMPOSITION FOR HEAT CYCLE SYSTEM, AND HEAT CYCLE SYSTEM AGC Inc. (JP) 2022-08-18 US disclosed
US-11339314-B2 Composition for heat cycle system, and heat cycle system AGC Inc. (JP) 2022-05-24 US disclosed
CN-106750349-B Polypeptide-modified polyamide-amine dendritic polymer and preparation method and application thereof 四川大学 2020-08-14 CN disclosed
US-20200188920-A1 METHODS AND SYSTEMS FOR IMPROVED DROPLET STABILIZATION 10X GENOMICS INC (US) 2020-06-18 US disclosed
EP-3642397-A1 METHODS AND SYSTEMS FOR IMPROVED DROPLET STABILIZATION 10X Genomics, Inc. (US) 2020-04-29 EP disclosed
CN-110799679-A Method and system for improving droplet stabilization 10X基因组学有限公司 2020-02-14 CN disclosed
US-5756869-A Method of preparing hydrofluorocarbon CENTRAL GLASS COMPANY LIMITED (JP) 1998-05-26 US disclosed
US-4147884-A Liquid phase oxidation of unsaturated aldehydes to corresponding acids ATLANTIC RICHFIELD COMPANY (US) 1979-04-03 US disclosed