Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368869 | 0.80 | IKZF2 (0.67) | IKZF1IKZF2 | |
| SCHEMBL20765621 | 0.80 | IKZF2 (0.67) | IKZF1IKZF2 | |
| SCHEMBL31158825 | 0.79 | IKZF1 (0.52) | IKZF1IKZF2 | |
| SCHEMBL31158642 | 0.79 | IKZF1 (0.52) | IKZF1IKZF2 | |
| SCHEMBL20766670 | 0.79 | IKZF2 (0.65) | IKZF1IKZF2 | |
| SCHEMBL1403510 | 0.78 | CRBN (0.58) | IKZF1IKZF2 | |
| SCHEMBL1403671 | 0.78 | CRBN (0.55) | IKZF1IKZF2 | |
| SCHEMBL31025764 | 0.78 | IKZF2 (0.55) | IKZF1IKZF2 | |
| SCHEMBL31025788 | 0.77 | IKZF2 (0.53) | IKZF1IKZF2 | |
| SCHEMBL30805375 | 0.77 | IKZF2 (0.69) | IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002397-A1 | SMALL MOLECULE DEGRADERS OF HELIOS AND METODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002397-A1 | SMALL MOLECULE DEGRADERS OF HELIOS AND METODS OF USE | IKZF2, IKZF1, HELZ | IKZF1 2/4885IKZF2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.