Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24860 | 1.00 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL23883 | 0.85 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL23884 | 0.85 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL24710 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25621 | 0.76 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL25622 | 0.76 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL1785151 | 0.68 | CA12 (0.45) | MAPT | |
| SCHEMBL1784055 | 0.68 | CA12 (0.45) | MAPT | |
| SCHEMBL24616 | 0.66 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL25790 | 0.63 | HTT (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |