Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123945 | 0.72 | CDC7 (0.44) | PTGS1PTGS2CDC7NR3C2 | |
| SCHEMBL24934670 | 0.71 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL3124363 | 0.69 | — | — | |
| SCHEMBL28779930 | 0.67 | PDCD1 (0.41) | PTGS1PTGS2ADRB1 | |
| SCHEMBL15456362 | 0.67 | ADRB1 (0.33) | NR3C2KDM4EADRB1 | |
| SCHEMBL24860283 | 0.66 | PTGS1 (0.34) | PTGS1PTGS2NR3C2KDM4EL3MBTL1 | |
| SCHEMBL31409376 | 0.65 | ADRB1 (0.35) | PTGS1ADRB1 | |
| SCHEMBL16285308 | 0.65 | CDC7 (0.54) | CDC7KDM4E | |
| SCHEMBL3133050 | 0.65 | ADRB1 (0.35) | PTGS2ADRB1 | |
| SCHEMBL31409374 | 0.64 | PLAT (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116301-A1 | FUSED TRICYCLIC COMPOUND AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 2023-01-11 | — | — | EP | disclosed |