Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.72 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.72 |
| ▸ | PHGDH | O43175 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26417331 | 1.00 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861807 | 0.93 | PTGER4 (0.62) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861730 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861806 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL26417363 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL26417308 | 0.89 | PTGER4 (0.73) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861881 | 0.89 | PTGER4 (0.73) | PTGER4PTGER2PHGDH | |
| SCHEMBL28692145 | 0.87 | PTGER4 (0.74) | PTGER4PTGER2 | |
| SCHEMBL28692146 | 0.86 | PTGER4 (0.67) | PTGER4PTGER2PHGDH | |
| SCHEMBL10122170 | 0.85 | PTGER4 (0.81) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116291-A1 | SYNTHESIS OF NOVEL EP4 ANTAGONIST AND USE IN CANCERS AND INFLAMMATIONS | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-01-11 | — | — | EP | disclosed |