Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | PRKDC | P78527 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | SRC | P12931 | 5/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | HCK | P08631 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | ATG7 | O95352 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 14/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10261498 | 0.78 | PIK3CD (0.53) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL868744 | 0.75 | PIK3CD (0.51) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL15826969 | 0.75 | PIK3CD (0.51) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL6926274 | 0.73 | PIK3CD (0.52) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL13925849 | 0.72 | PIK3CD (0.46) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL19500706 | 0.72 | PIK3CD (0.48) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL14577797 | 0.71 | KDR (0.43) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL19732713 | 0.70 | RET (0.60) | PIK3CDKDRSRCRETLCK | |
| SCHEMBL15826968 | 0.70 | PIK3CD (0.73) | PIK3CDPRKDCKDRSRCABL1 | |
| SCHEMBL19732764 | 0.70 | RET (0.61) | PIK3CDPRKDCKDRSRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116302-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | Tianjin Jikun Medical Technology Co., Ltd. (CN) | 2023-01-11 | — | — | EP | disclosed |