Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 8/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925849 | 0.80 | PIK3CD (0.46) | KDRFGFR2BRAFABL1BCR | |
| SCHEMBL19500706 | 0.72 | PIK3CD (0.48) | KDRBRAFABL1BCRSRC | |
| SCHEMBL24862018 | 0.71 | PIK3CD (0.47) | KDRABL1SRCEGFREPHB4 | |
| SCHEMBL10261498 | 0.67 | PIK3CD (0.53) | KDRBRAFABL1SRCEGFR | |
| SCHEMBL130452 | 0.66 | PIK3CD (0.46) | KDRFGFR2ABL1SRCEGFR | |
| SCHEMBL1848609 | 0.65 | ATG7 (0.43) | KDRFGFR2ABL1SRCEGFR | |
| SCHEMBL6926274 | 0.65 | PIK3CD (0.52) | KDRABL1SRCEGFREPHB4 | |
| SCHEMBL868744 | 0.65 | PIK3CD (0.51) | KDRABL1SRCEGFREPHB4 | |
| SCHEMBL15826969 | 0.65 | PIK3CD (0.51) | KDRABL1SRCEGFREPHB4 | |
| SCHEMBL1847885 | 0.62 | ATG7 (0.43) | KDRFGFR2ABL1SRCJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179905-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2007-02-20 | — | — | US | disclosed |