Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004036 | 0.88 | NPC1 (0.54) | NPC1LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL30719583 | 0.88 | NPC1 (0.54) | NPC1LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL21473892 | 0.85 | BRAF (0.46) | BRAFLMNATNNI3K | |
| SCHEMBL3001568 | 0.83 | BRAF (0.53) | BRAFTNNI3KEGFRTTBK1TTBK2 | |
| SCHEMBL2995233 | 0.81 | BRAF (0.51) | BRAFHTTTNNI3KEGFRKDR | |
| SCHEMBL2995190 | 0.81 | BRAF (0.52) | BRAFHTTTNNI3KEGFRSRC | |
| SCHEMBL3001378 | 0.80 | NFKB1 (0.46) | EGFR | |
| SCHEMBL5839044 | 0.78 | BRAF (0.54) | BRAFSMN1; SMN2 | |
| SCHEMBL5839451 | 0.78 | SYK (0.47) | EGFR | |
| SCHEMBL3010051 | 0.77 | SMN1; SMN2 (0.45) | NPC1LMNAHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4115882-A1 | COMPOUNDS FOR IMPROVING MRNA SPLICING | The General Hospital Corporation (US) | 2023-01-11 | — | — | EP | disclosed |