Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513362 | 0.80 | MAPT (0.53) | MAPTKMT2APTGDR2THRBHTT | |
| SCHEMBL17784762 | 0.78 | MAPT (0.45) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL17784859 | 0.76 | MAPT (0.47) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL22491805 | 0.76 | MAPT (0.44) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL19939512 | 0.76 | BRD4 (0.53) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL19501371 | 0.76 | MAPT (0.50) | MAPTKMT2APTGDR2THRBHTT | |
| SCHEMBL19513477 | 0.76 | MAPT (0.41) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL13906422 | 0.75 | LMNA (0.54) | KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28894823 | 0.73 | MAPT (0.43) | MAPTBRD4BRD2BRD3BRDT | |
| SCHEMBL8276897 | 0.73 | MEN1 (0.50) | MAPTKMT2APTGDR2THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116299-A1 | HETEROCYCLIC COMPOUND | Medshine Discovery Inc. (CN) | 2023-01-11 | — | — | EP | disclosed |