Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 13/20 | 0.42 |
| ▸ | CA2 | P00918 | 13/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864460 | 0.84 | BLM (0.62) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL27291342 | 0.83 | BLM (0.49) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL16995563 | 0.82 | BLM (0.43) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL29594603 | 0.81 | TLR2 (0.41) | CA1CA2TLR2TLR1CA12 | |
| SCHEMBL21611677 | 0.81 | TLR2 (0.41) | CA1CA2TLR2TLR1CA12 | |
| SCHEMBL25330597 | 0.81 | TLR2 (0.41) | CA1CA2TLR2TLR1CA12 | |
| SCHEMBL15676126 | 0.80 | TLR2 (0.38) | CA1CA2TLR2TLR1CA12 | |
| SCHEMBL29344308 | 0.80 | BLM (0.51) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL15508735 | 0.80 | BLM (0.45) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL16995569 | 0.80 | BLM (0.45) | BLMPMP22HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |