Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 17/20 | 0.47 |
| ▸ | CA2 | P00918 | 17/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252347 | 0.90 | BLM (0.46) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL5547592 | 0.87 | BLM (0.50) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL8089127 | 0.86 | BLM (0.47) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL24024217 | 0.86 | BLM (0.47) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL24024197 | 0.86 | BLM (0.47) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL27291342 | 0.85 | BLM (0.49) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL24864455 | 0.85 | BLM (0.49) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL3153101 | 0.85 | DNM1 (0.49) | BLMPMP22HSD17B10 | |
| SCHEMBL27291507 | 0.83 | BLM (0.46) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL3154287 | 0.82 | DGKA (0.49) | BLMPMP22HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |