Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 17/20 | 0.40 |
| ▸ | CA2 | P00918 | 17/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864347 | 0.84 | BLM (0.43) | BLMPMP22HSD17B10CA1CA2 | |
| SCHEMBL944740 | 0.82 | BLM (0.36) | BLMPMP22HSD17B10 | |
| SCHEMBL26292093 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL30980495 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL19475654 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL7676443 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL31395742 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL12092180 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL22717025 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR | |
| SCHEMBL7677587 | 0.81 | TLR2 (0.34) | BLMPMP22HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |