Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29342071 | 0.92 | FURIN (0.43) | FURINBACE1S1PR1S1PR3 | |
| SCHEMBL24864662 | 0.92 | FURIN (0.44) | FURINSMN1; SMN2BACE1HTT | |
| SCHEMBL29339858 | 0.92 | FURIN (0.43) | FURINSMN1; SMN2HTT | |
| SCHEMBL29342072 | 0.90 | FURIN (0.45) | FURINSMN1; SMN2OPRD1HTT | |
| SCHEMBL17133811 | 0.89 | FURIN (0.45) | FURINSMN1; SMN2HTT | |
| SCHEMBL17133812 | 0.89 | FURIN (0.45) | FURINSMN1; SMN2HTT | |
| SCHEMBL24864480 | 0.88 | NPY4R (0.42) | FURINHTT | |
| SCHEMBL24864665 | 0.88 | NPY4R (0.44) | FURIN | |
| SCHEMBL31559005 | 0.88 | FURIN (0.41) | FURINSMN1; SMN2HTT | |
| SCHEMBL31047760 | 0.88 | FURIN (0.41) | FURINSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |