Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.44 |
| ▸ | NPY1R | P25929 | 5/20 | 0.44 |
| ▸ | NPY2R | P49146 | 4/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | FURIN | P09958 | 5/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864480 | 0.99 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RFURIN | |
| SCHEMBL24864584 | 0.92 | FURIN (0.43) | FURINKLKB1PDFNMT2NMT1 | |
| SCHEMBL20435138 | 0.92 | FURIN (0.45) | FURINKLKB1PDF | |
| SCHEMBL29342070 | 0.91 | FURIN (0.42) | FURINKLKB1PDFNMT2NMT1 | |
| SCHEMBL29345943 | 0.91 | FURIN (0.42) | FURINKLKB1PDFNMT2NMT1 | |
| SCHEMBL24864664 | 0.90 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29339858 | 0.90 | FURIN (0.43) | NPY4RNPY1RNPY2RNPY5RFURIN | |
| SCHEMBL29342071 | 0.89 | FURIN (0.43) | FURIN | |
| SCHEMBL15692124 | 0.88 | NMT2 (0.45) | NPY4RNPY1RNPY2RNPY5RFURIN | |
| SCHEMBL24864481 | 0.88 | FURIN (0.43) | FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |