SCHEMBL31559005

SCHEMBL31559005

CC(C)[C@H](NC(=O)[C@@H](N)CS(=O)(=O)O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FURIN P09958 9/20 0.41
HTT P42858 1/20 0.37
NPY4R P50391 6/20 0.37
NPY1R P25929 4/20 0.37
NPY2R P49146 2/20 0.37
NPY5R Q15761 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ADAM10 O14672 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP12 P39900 1/20 0.36
MMP14 P50281 1/20 0.36
ADAM8 P78325 1/20 0.36
ADAM17 P78536 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31047760 0.93 FURIN (0.41) FURINHTTNPY4RNPY1RNPY2R
SCHEMBL29339858 0.90 FURIN (0.43) FURINHTTNPY4RNPY1RNPY2R
SCHEMBL24864481 0.88 FURIN (0.43) FURINHTTSMN1; SMN2
SCHEMBL29342071 0.87 FURIN (0.43) FURIN
SCHEMBL24864480 0.87 NPY4R (0.42) FURINHTTNPY4RNPY1RNPY2R
SCHEMBL24864665 0.86 NPY4R (0.44) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL31558978 0.86 FURIN (0.41) FURINHTTNPY4RNPY1RNPY2R
SCHEMBL31559049 0.85 CA2 (0.43) FURIN
SCHEMBL29345954 0.85 FURIN (0.44) FURINHTTSMN1; SMN2
SCHEMBL24297455 0.85 FURIN (0.43) FURINHTTNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124317-A2 Antibody Drug Conjugates BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
US-20250135026-A1 Antibody Drug Conjugates BEIGENE SWITZERLAND GMBH (CH) 2025-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124317-A2 Antibody Drug Conjugates SLC3A2, SLC7A1, SLC43A1 FURIN 1498/4885HTT 2334/4885NPY4R 1409/4885
US-20250135026-A1 Antibody Drug Conjugates CD22, FCGR2A, FCGR3B FURIN 398/4885HTT 2664/4885NPY4R 4267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.