Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201178 | 0.87 | PDK1 (0.42) | KDM4EPDK1PDK2PDK3PDK4 | |
| SCHEMBL24864501 | 0.85 | GAA (0.38) | TLR2TLR1ALDH1A1RAB9AALOX12 | |
| SCHEMBL24864502 | 0.85 | TLR2 (0.40) | TLR2TLR1PDK1PDK2PDK3 | |
| SCHEMBL27291337 | 0.83 | KDM4E (0.42) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9135679 | 0.78 | ALDH1A1 (0.47) | KDM4EPDK1PDK2PDK3PDK4 | |
| SCHEMBL30063253 | 0.74 | SMN1; SMN2 (0.41) | TLR2TLR1KDM4EALDH1A1RAB9A | |
| SCHEMBL27420943 | 0.73 | TLR2 (0.38) | TLR2TLR1KDM4EALDH1A1LMNA | |
| SCHEMBL17229457 | 0.73 | TLR2 (0.38) | TLR2TLR1KDM4EALDH1A1LMNA | |
| SCHEMBL31231100 | 0.73 | TLR2 (0.38) | TLR2TLR1KDM4EALDH1A1LMNA | |
| SCHEMBL26689416 | 0.73 | TLR2 (0.38) | TLR2TLR1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |